Hartil Amlo is a combination medication that is used to normalize blood pressure and restore blood circulation.
International non-proprietary name
In Latin, the drug is called HARTIL AMLO and is registered under such INN.
Hartil Amlo is a combination medication.
International code C09AA05.
Forms of release and composition
The drug is available in the form of gelatin capsules of 5 mg and 10 mg of active active ingredient. The active active ingredient is ramipril (Ramiprilum). This is a chemical compound, which is a white powder, soluble in buffer solutions and organic solvents. Auxiliary substances - amlodipine, microcellulose, crospovidone, hypromellose.
The drug belongs to ACE inhibitors (angiotensin ACP). These are substances that block the conversion of angiotensin 1 to active angiotensin 2. As a result, during a long course of treatment with the drug, blood pressure decreases and the load on the heart muscle decreases. Due to this drug prevents cardiovascular diseases and preserves the contractility of the myocardium.
After oral administration, the active substance is absorbed within 1-2 hours. The maximum peak of exposure is reached after 4 hours, and the drug acts in the body for about a day. Thus, with a course of treatment and daily administration of Hartil, ramipril plasma concentration increases, which has an antihypertensive effect and prevents the consequences of heart failure.
With a long course of treatment with Hartil Amlo, blood pressure is reduced and the load on the heart muscle is reduced.
Active metabolism occurs in the digestive tract, and the substance is excreted by the kidneys and intestines. The half-life is 24 hours. Efficiency and bioavailability depends on many factors, including the patient's age and the presence or absence of chronic diseases. Concentrated in liver esterases, blood, saliva, milk, pancreas.
Indications for use
Capsules have a broad spectrum of ramipril and are prescribed for the following indications:
- arterial hypertension - a condition of chronic high blood pressure;
- mitral valve prolapse;
- used in malignant hyperthermia to alleviate the condition;
- heart failure, in which the work of the whole organism is disrupted due to insufficient blood circulation and oxygenation of organs and systems;
- angina, ischemia;
- consequence of myocardial infarction to prevent recurrence and reduce the load on the heart muscle;
- prevention of stroke in ischemic heart disease.
In order not to harm your body, before using the drug, you need to familiarize yourself with a number of contraindications:
- individual intolerance to the components of the composition;
- impaired renal function;
- disruption of the liver and organs of the urogenital system;
- aortic stenosis of the kidneys;
- allergic reactions;
- childbearing and lactation period;
- age up to 15 years.
Use with caution in gynecomastia and other gynecological diseases.
How to take Hartil Amlo
The doctor prescribes the drug, depending on the individual characteristics of the patient.
In diabetes, a minimum dosage is prescribed if the potential effect exceeds the potential harm.
Side effects of Hartila Amlo
Like any drug, Hartil causes a number of adverse reactions in case of intolerance or misuse.
Stomatitis, nausea, vomiting, heartburn, pancreatitis, intestinal edema, diarrhea, pain in the intestines and pancreas, loss of appetite.
On the part of the gastrointestinal tract, Hartil can cause nausea.
Anemia, a violation of the number of blood bodies, thrombocytopenia, leukocytopenia, a decrease in red blood cells and hemoglobin protein, bone marrow suppression.
central nervous system
Irritability, insomnia, stress, dizziness, muscle spasms, decreased efficacy, fatigue after sleep.
On the part of the respiratory system
Dyspnea, dry cough, development of asthma, chronic sinusitis.
From the genitourinary system
The development of renal failure, decrease in urine volume, metabolic disorders.
Itching of the skin, urticaria, angioedema, conjunctivitis, discoloration of the skin.
Influence on ability to operate mechanisms
The drug can affect the central nervous system, cause drowsiness, reduce concentration. In this regard, you should find yourself out of working on automatic equipment or driving vehicles.
The drug Hartil Amlo can affect the ability to drive a vehicle.
The drug intake and dosage depend on many factors - the type of disease, the age and condition of the patient, the presence of chronic pathologies, body weight. In heart failure and hypertension, 2.5 mg of the drug is taken per day. Every 2 weeks the dosage can be gradually increased. Capsules washed down with plenty of water.
Use in old age
People after 70 should start taking Chartil at a dosage of 1.25 mg. The dose is adjusted individually according to the dynamics of changes in blood pressure and the general condition of the body.
The appointment of Hartila Amlo children
Till 15 years, taking the drug to children is strictly forbidden, since studies have not been conducted.
Use during pregnancy and lactation
At the II and III trimester, this tool is prohibited to take. During the first trimester, use of the Charter is possible only in case of emergency. When treating during lactation, it is recommended to switch to artificial feeding.
Children up to 15 years of age are strictly prohibited to take the drug, since no studies have been conducted.
Overdose of Hartila Amlo
Overdose causes the following symptoms:
- lower blood pressure;
- headache, tinnitus;
- nausea, vomiting, abdominal pain;
- violation of water and electrolyte balance.
If you feel unwell, you need to immediately rinse the stomach, take the sorbent (activated carbon or Enterosgel) and seek medical help.
Interaction with other drugs
When taken concurrently with diuretics and other hypertensive drugs, excessive lowering of blood pressure is possible.
If you combine antihypertensive drugs with nonsteroidal anti-inflammatory drugs, the effect decreases, and there will be little benefit from the tool.
When taking lithium-containing drugs in combination with Hartil increases the concentration of lithium in the blood.
It is not recommended to use together with products containing potassium in the composition in order not to exceed the level of potassium in the body.
If for some reason capsules cannot be taken, you can replace them with Hungarian, American or Russian preparations of a similar effect:
- on the basis of ramipril and amlodipine: capsules Bi-Ramag, Sumilar, Tritatse-A;
- on the basis of amlodipine and lisinopril: tablets Amapil-L, Amlipin, Equator;
- on the basis of perindopril: Amlessa, Bi-Prestarium, Viakoram;
- based on lercanidipine and enalapril: Coriprene, Lerkamen, Enap L Combi.
Experts do not recommend changing the drugs themselves, so as not to harm the health. Before replacing, you should consult a doctor.
Pharmacy vacation terms
Capsules are available only on prescription.
Can I buy without a prescription
Without a prescription can be purchased at an online pharmacy. It is important to purchase goods on proven resources in order not to fall into the tricks of fraudsters.
Price for Hartil Amlo
The cost of the drug depends on the form of release and the point of sale. The average price on the territory of the Russian Federation is 15-30 rubles.
Capsules are available only on prescription.
Drug storage conditions
Store in a dark place at room temperature. For safety, keep away from children.
Drugs can be stored 24 months from the production date.
OJSC "Pharmaceutical plant EGIS". 1106, Budapest, ul. Keresturi, 30-38, Hungary.
Reviews of Hartil Amlo
Over the years, the drug has proven its effectiveness and efficacy, as evidenced by reviews not only of specialists, but also of patients.
Alexander Ivanovich, Moscow
The drug is one of the most effective for the treatment and prevention of heart disease and restore blood pressure. If there are no contraindications, I always prescribe it for the prevention of recurrent myocardial infarction and stroke.
Tamara Nikolaevna, 70 years old, Krasnodar
Both my husband and I suffer from heart failure. For several years we have been drinking the Chartila course twice a year. The drug is effective, does not cause side effects, quickly lowers blood pressure, relieves headache, swelling. Heart works without interruption, we feel younger by 20 years.